The answer to the toughest clue ever given in the New York Times' cryptic crossword puzzle is senselessness. What was the single-letter clue?
Etymology, Etymology, and more Etymology
as well as grammar, usage, euphemism, slang, jargon, semantics (meaning), linguistics, neologism, idiom, word origin, syntax, dialect, lexicon (vocabulary), diction, pidgin, synonym, antonym, homonym, cant, argot, lingo, and redundancy.

The critically-acclaimed board game MooT consists of tough questions about the nuances of the English language.
Answer: e
sense less ness = e
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